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Low immunoglobulin G3 levels in wheezy children.

Authors
  • Ones, U
  • Güler, N
  • Somer, A
  • Salman, N
  • Yalçin, I
Type
Published Article
Journal
Acta paediatrica (Oslo, Norway : 1992)
Publication Date
Apr 01, 1998
Volume
87
Issue
4
Pages
368–370
Identifiers
PMID: 9628287
Source
Medline
License
Unknown

Abstract

This study aimed to investigate the prevalence of IgG subclass deficiency in wheezy children aged <3 y. Serum levels of IgA, IgE and IgG subclasses were measured in 310 children with recurrent wheezing and in 100 healthy controls. IgG3 levels were below the normal lower limit in 123 (39.6%) patients. This finding may reflect delayed maturation of the immune system, predisposing young children <3 y of age to wheezing.

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