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Low-dose rosuvastatin improves arterial stiffness in high-risk Japanese patients with dyslipdemia in a primary prevention group.

Authors
  • Hongo, Minoru
  • Kumazaki, Setsuo
  • Izawa, Atsushi
  • Hidaka, Hiroya
  • Tomita, Takeshi
  • Yazaki, Yoshikazu
  • Kinoshita, Osamu
  • Ikeda, Uichi
Type
Published Article
Journal
Circulation journal : official journal of the Japanese Circulation Society
Publication Date
Jan 01, 2011
Volume
75
Issue
11
Pages
2660–2667
Identifiers
PMID: 21857142
Source
Medline
License
Unknown

Abstract

Low-dose rosuvastatin would be more effective than fluvastatin in improving arterial stiffness in high-risk Japanese patients with dyslipidemia. The results suggest that improvement in arterial stiffness by rosuvastatin mainly depends on its strong lipid-lowering effects, whereas that by fluvastatin is strongly dependent on the pleiotropic effects, especially an anti-inflammatory action.

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