Affordable Access

deepdyve-link
Publisher Website

Long-term use of proton pump inhibitors, dose-response relationship and associated risk of ischemic stroke and myocardial infarction.

Authors
  • Sehested, T S G1
  • Gerds, T A1, 2
  • Fosbøl, E L3
  • Hansen, P W1, 4
  • Charlot, M G5
  • Carlson, N1, 6
  • Hlatky, M A4
  • Torp-Pedersen, C7
  • Gislason, G H1, 3, 8
  • 1 Department of Cardiovascular Epidemiology and Research, The Danish Heart Foundation, Copenhagen K, Denmark. , (Denmark)
  • 2 Department of Biostatistics, Copenhagen University, Copenhagen, Denmark. , (Denmark)
  • 3 The Heart Centre, Copenhagen University Hospital, Rigshospitalet, Denmark. , (Denmark)
  • 4 Department of Health Research and Policy, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA.
  • 5 Department of Cardiology, Copenhagen University Hospital, Herlev and Gentofte, Denmark. , (Denmark)
  • 6 Department of internal medicine, Gastroenterology section, Holbaek Hospital, Holbaek, Denmark. , (Denmark)
  • 7 Department of Health, Science and Technology, Department of Cardiology and Epidemiology/Biostatistics, Aalborg University, Aalborg University Hospital, Hellerup, Denmark. , (Denmark)
  • 8 The National Institute of Public Health, University of Southern Denmark, Copenhagen, Denmark. , (Denmark)
Type
Published Article
Journal
Journal of internal medicine
Publication Date
Oct 12, 2017
Identifiers
DOI: 10.1111/joim.12698
PMID: 29024109
Source
Medline
Keywords
License
Unknown

Abstract

Use of PPIs was associated with increased risks of first-time ischemic stroke and MI, particularly amongst long-term users and at high doses.

Report this publication

Statistics

Seen <100 times