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Long-term survival in patients with supratentorial glioblastoma

Authors
  • Salvati, Maurizio1
  • Cervoni, Luigi1
  • Artico, Marco2
  • Caruso, Riccardo2
  • Gagliardi, Franco Maria2
  • 1 IRCCS, Mediterranean Neuromedical Institute of Neurosciences, Pozzilli (Is)
  • 2 University of Rome, Faculty of Pharmacy, 'La Sapienza', Italy
Type
Published Article
Journal
Journal of Neuro-Oncology
Publisher
Springer-Verlag
Publication Date
Jan 01, 1998
Volume
36
Issue
1
Pages
61–64
Identifiers
DOI: 10.1023/A:1017926603341
Source
Springer Nature
Keywords
License
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Abstract

The authors report 11 patients with cerebral glioblastoma who lived at least 5 years after their initial diagnosis. There were 6 female and 5 male; the mean age was 39 years (range 24–55 years). All patients were treated surgically and postoperatively received whole-brain radiotherapy and chemotherapy. Five patients (45%) presented local recurrences after an average interval of 3.9 years from treatment. At average follow-up of 9 years (range 5–14 years), 7 patients (64%) were alive after an average interval of 8.1 years; 4 patients (36%) died from local relapse. Survival was influenced by patient age and, to a lesser degree, by treatment. A review of the literature, together with our own series, suggest that death from recurrence disease is unusual in glioblastoma patients who survive more than 5 years.

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