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Long-Term Survival after Acute Myocardial Infarction in Lithuania during Transitional Period (1996–2015): Data from Population-Based Kaunas Ischemic Heart Disease Register

Authors
  • Radisauskas, Ricardas1, 2
  • Kirvaitiene, Jolita1
  • Bernotiene, Gailutė2
  • Virviciutė, Dalia2
  • Ustinaviciene, Ruta1
  • Tamosiunas, Abdonas2, 3
  • 1 Department of Environmental and Occupational Medicine, Medical Academy, Lithuanian University of Health Sciences, LT-47181 Kaunas, Lithuania
  • 2 Institute of Cardiology, Medical Academy, Lithuanian University of Health Sciences, LT-50103 Kaunas, Lithuania
  • 3 Department of Preventive Medicine, Medical Academy, Lithuanian University of Health Sciences, LT-47181 Kaunas, Lithuania
Type
Published Article
Journal
Medicina
Publisher
MDPI
Publication Date
Jul 09, 2019
Volume
55
Issue
7
Identifiers
DOI: 10.3390/medicina55070357
PMID: 31324034
PMCID: PMC6681332
Source
PubMed Central
Keywords
License
Green

Abstract

Background and Objective : There is a lack of reliable epidemiological data on the long-term survival after acute myocardial infarction (AMI) in the Lithuanian population. The aim of the study was to evaluate the long-term (36 months) survival after AMI among persons aged 25–64 years, who had experienced AMI in four time-periods 1996, 2003–2004, 2008, and 2012. Material and Methods : The source of the data was Kaunas population-based Ischemic heart disease (IHD) register. Long-term survival after AMI (36 months) was evaluated using the Kaplan–Meier method. The survival curves significantly differed when p < 0.05. Hazard ratio for all-cause mortality and their 95% CIs, adjusted for baseline characteristics, were estimated with the Cox proportional hazards regression model. Results: The analysis of data on 36 months long-term survival among Kaunas population by sex and age groups showed that the survival rates among men and women were 83.4% and 87.6%, respectively ( p < 0.05) and among 25–54 years-old and 55–64 years-old persons, 89.2% and 81.7%, respectively ( p < 0.05). The rates of long-term survival of post-AMI Kaunas population were better in past periods than in first period. According to the data of the Kaplan-Meier survival analysis, long-term survival of 25 to 64-year-old post-AMI Kaunas population was without significantly difference in 1996, 2003–2004, 2008 and 2012 (Log-rank = 6.736, p = 0.081). The adjusted risk of all-cause mortality during 36 months among men and 25 to 54-year-old patients was on the average by 35% and 60% lower in 2012 than in 1996, respectively. Conclusion : It was found that 36 months survival post MI among women and younger (25–54 years) persons was significant better compared to men and older (55–64 years) persons. Long-term survival among 55 to 64-year-old post-AMI Kaunas population had a tendency to decrease during last period, while among 25–54 years old persons long-term survival was without significant changes. The results highlight the fact that AMI survivors, especially in youngest age, remain a high-risk group and reinforce the importance of primary and secondary prevention for the improvement of long-term prognosis of AMI patients.

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