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Long-term survival in adult mediastinal neuroblastoma

Authors
  • Shimizu, Mayumi1
  • Shimizu, Toshihide1
  • Adachi, Takashi1
  • Nishiuchi, Masaki1
  • Kanzaki, Masato1
  • Onuki, Takamasa1
  • 1 Tokyo Women's Medical University, Department of Surgery I, 8-1, Kawadacho, Shinjuku-ku, Tokyo, 162-8666, Japan , Tokyo (Japan)
Type
Published Article
Journal
The Japanese Journal of Thoracic and Cardiovascular Surgery
Publisher
Springer-Verlag
Publication Date
Jul 01, 2003
Volume
51
Issue
7
Pages
326–329
Identifiers
DOI: 10.1007/BF02719388
Source
Springer Nature
Keywords
License
Yellow

Abstract

Neuroblastoma rarely occurs in adults, in whom prognosis is poor. Here we report on the effective use of multimodal therapy to achieve long-term survival in adult mediastinal neuroblastoma. In a 33-year-old male with severe pain radiating from the left hypochondrium to the back area, no abnormal shadow was detected on first examination; the shadow appeared in chest X-ray only 10 months later when the severe pain recurred. The patient was then referred to our department for further examination. Chest X-rays and chest CT scans revealed a posterior mediastinal mass beside the thoracic vertebrae. Diagnosis was confirmed after surgical resection, which was followed by outpatient adjuvant therapy through radiation and chemotherapy. The patient has survived 8 years and 8 months without recurrence or metastasis.

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