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Long-term follow-up of endocrine function among young children with newly diagnosed malignant central nervous system tumors treated with irradiation-avoiding regimens.

Authors
  • Cochrane, Anne M1
  • Cheung, Clement2
  • Rangan, Kasey1
  • Freyer, David1
  • Nahata, Leena3
  • Dhall, Girish1
  • Finlay, Jonathan L4
  • 1 Division of Hematology and Oncology, Children's Hospital Los Angeles, California.
  • 2 Division of Endocrinology, Children's Hospital Los Angeles, California.
  • 3 Division of Endocrinology, Nationwide Children's Hospital and The Ohio State University, Columbus, Ohio.
  • 4 Division of Hematology, Oncology and BMT, Nationwide Children's Hospital and The Ohio State University, Columbus, Ohio.
Type
Published Article
Journal
Pediatric Blood & Cancer
Publisher
Wiley (John Wiley & Sons)
Publication Date
Nov 01, 2017
Volume
64
Issue
11
Identifiers
DOI: 10.1002/pbc.26616
PMID: 28475292
Source
Medline
Keywords
License
Unknown

Abstract

These findings demonstrate that the use of relatively brief, intensive chemotherapy regimens including marrow-ablative chemotherapy with AuHCR results in fewer endocrine sequelae than treatment schemes utilizing CNS irradiation.

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