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Long-term endothelial cell loss with the iris-claw intraocular phakic lenses (Artisan®).

Authors
  • Galvis, Virgilio1, 2, 3
  • Villamil, John F1, 4
  • Acuña, María Fernanda2, 3
  • Camacho, Paul A2, 3
  • Merayo-Lloves, Jesús5, 6
  • Tello, Alejandro7, 8, 9
  • Zambrano, Sandra Lizeth2, 4
  • Rey, Juan José3
  • Espinoza, Juan Vicente2, 4
  • Prada, Angélica María1
  • 1 Centro Oftalmológico Virgilio Galvis, FOSCAL Internacional, Calle 158 20-95, Consultorio 301, Torre C, Floridablanca, Colombia. , (Colombia)
  • 2 Ophthalmology Department, Fundación Oftalmológica de Santander FOSCAL, Floridablanca, Colombia. , (Colombia)
  • 3 Faculty of Health Sciences, Universidad Autónoma de Bucaramanga, Bucaramanga, Colombia. , (Colombia)
  • 4 Faculty of Health Sciences, Universidad Industrial de Santander, Bucaramanga, Colombia. , (Colombia)
  • 5 Instituto Universitario Fernández-Vega, Oviedo, Spain. , (Spain)
  • 6 Ophthalmology Department, Universidad de Oviedo, Oviedo, Spain. , (Spain)
  • 7 Centro Oftalmológico Virgilio Galvis, FOSCAL Internacional, Calle 158 20-95, Consultorio 301, Torre C, Floridablanca, Colombia. [email protected] , (Colombia)
  • 8 Ophthalmology Department, Fundación Oftalmológica de Santander FOSCAL, Floridablanca, Colombia. alejandrotell[email protected] , (Colombia)
  • 9 Faculty of Health Sciences, Universidad Autónoma de Bucaramanga, Bucaramanga, Colombia. [email protected] , (Colombia)
Type
Published Article
Journal
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie
Publication Date
Dec 01, 2019
Volume
257
Issue
12
Pages
2775–2787
Identifiers
DOI: 10.1007/s00417-019-04506-9
PMID: 31659458
Source
Medline
Keywords
Language
English
License
Unknown

Abstract

To evaluate the endothelial cell loss in patients with iris-claw phakic lenses (Artisan®) in a long-term follow-up. We analyzed the medical records of patients who had undergone iris-claw phakic lens implantation and who had at least 5 years of follow-up. We included 67 eyes with myopic errors (follow-up 9.6 ± 3.0 years) and 10 eyes with mixed astigmatism or hyperopic errors (follow-up 8.8 ± 2.5 years). The mean total endothelial density loss at the last follow-up visit was 18.5% ± 17.0% and 10.5% ± 12.3%, respectively. 29.9% of the eyes in the myopic group and 20% in the hyperopic group lost more than 25% of the preoperative endothelial cell density. During the postoperative follow-up period, 60.8% of the eyes in the myopic group and 40% of the eyes in the hyperopic group lost a higher percentage than the expected physiological loss. Two eyes in the myopic group (3.0%) had a final cell density of less than 1200 cells/mm2. None of the variables studied had a statistically significant association with the percentage of annual endothelial loss in the postoperative period. Three phakic lenses were explanted: two by cataract and one by cataract and severe decrease of the endothelial density (862 cells/mm2). There is a significant endothelial cell loss in a low percentage of the eyes with Artisan® lenses in the long term, and it can decrease to critical levels. Periodic endothelial density evaluations are required for these patients. The selection criteria of surgical candidates could be reevaluated.

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