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Longitudinal cognitive decline in subcortical ischemic vascular disease--the LADIS Study.

Authors
  • Jokinen, Hanna
  • Kalska, Hely
  • Ylikoski, Raija
  • Madureira, Sofia
  • Verdelho, Ana
  • van der Flier, Wiesje M
  • Scheltens, Philip
  • Barkhof, Frederik
  • Visser, Marieke C
  • Fazekas, Franz
  • Schmidt, Reinhold
  • O'Brien, John
  • Waldemar, Gunhild
  • Wallin, Anders
  • Chabriat, Hugues
  • Pantoni, Leonardo
  • Inzitari, Domenico
  • Erkinjuntti, Timo
Type
Published Article
Journal
Cerebrovascular Diseases
Publisher
S. Karger AG
Publication Date
Jan 01, 2009
Volume
27
Issue
4
Pages
384–391
Identifiers
DOI: 10.1159/000207442
PMID: 19276621
Source
Medline
License
Unknown

Abstract

SIVD, as a manifestation of cerebral small vessel disease, is related to progressive cognitive impairment and a considerable risk of developing dementia. SIVD seems to specifically contribute to the deterioration of psychomotor speed, executive control, and global cognitive function.

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