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Long term reproducibility of urodynamic investigations in healthy fertile females.

Authors
  • Sørensen, S
  • Gregersen, H
  • Sørensen, S M
Type
Published Article
Journal
Scandinavian journal of urology and nephrology. Supplementum
Publication Date
Jan 01, 1988
Volume
114
Pages
35–41
Identifiers
PMID: 3201166
Source
Medline
License
Unknown

Abstract

The long term reproducibility of uroflowmetry, urethral pressure profilometry, cystometry and pressure-flow studies was evaluated in 10 healthy fertile female volunteers over a two year period. All parameters were unchanged, except for an increase in the detrusor pressure. The volume at first sensation, the maximal cystometric capacity and the maximum flow rate, had a coefficience of variation (CV) of 24%, 15% and 21% respectively. The compliance and the opening time however showed a considerably higher CV. Several parameters showed a larger intra individual standard variation (SD) than the interindividual SD, indicating that these parameters should be interpreted with great care. Repetition of the investigations showed in this small material a reduction in the standard error of the mean (SEM). Repeating the investigation reduces the number of patients needed in a clinical trial to obtain a statistically significant change. The study showed that urodynamic investigation is a reliable tool in evaluation of patients over a period of years.

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