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Long-term evolution and determinants of renal function in HIV-infected patients who began receiving combination antiretroviral therapy in 1997-1999, ANRS CO8 APROCO-COPILOTE.

Authors
  • Leport, Catherine
  • Bouteloup, Vincent
  • Rossert, Jérôme
  • Garré, Michel
  • Iordache, Laura
  • Dellamonica, Pierre
  • Herson, Serge
  • Raffi, François
  • Chêne, Geneviève
Type
Published Article
Journal
Clinical Infectious Diseases
Publisher
Oxford University Press
Publication Date
Dec 15, 2009
Volume
49
Issue
12
Pages
1950–1954
Identifiers
DOI: 10.1086/648445
PMID: 19911986
Source
Medline
License
Unknown

Abstract

Among 1121 patients (90% Caucasian) infected by the human immunodeficiency virus (HIV), the glomerular filtration rate increased (+0.72 mL/min/1.73 m(2)/month) from treatment initiation to month 16 (the rate increase was lower among men and those with low body mass index, AIDS, or receipt of indinavir), then remained stable up to 7 years. Kidney function should be monitored in patients previously exposed to indinavir.

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