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Long Non-Coding RNAs in the Regulation of Gene Expression: Physiology and Disease

Authors
  • Fernandes, Juliane C. R.
  • Acuña, Stephanie M.
  • Aoki, Juliana I.
  • Floeter-Winter, Lucile M.
  • Muxel, Sandra M.
Publication Date
Feb 17, 2019
Source
MDPI
Keywords
Language
English
License
Green
External links

Abstract

however, the analysis of transcriptomes for their functional characterization remains a challenge. Here, we review some important aspects of lncRNA biology, focusing on their role as regulatory elements in gene expression modulation during physiological and disease processes, with implications in host and pathogens physiology, and their role in immune response modulation.

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