Affordable Access

Locust adipokinetic hormone stimulates lipid mobilization in Manduca sexta.

Authors
  • Shapiro, J P
  • Law, J H
Type
Published Article
Journal
Biochemical and biophysical research communications
Publication Date
Sep 30, 1983
Volume
115
Issue
3
Pages
924–931
Identifiers
PMID: 6626231
Source
Medline
License
Unknown

Abstract

Adipokinetic hormone, a decapeptide isolated from the locust, stimulates mobilization of diacylglycerols from the locust fat body and loading of the lipid transport protein, lipophorin. Injection of the synthetic locust adipokinetic hormone into a sphinx moth, Manduca sexta, causes lipid loading of lipophorin. The lipophorin decreases in density from 1.11 to 1.06 g/ml, and a soluble protein from the hemolymph (apolipophorin III) associates with the lipophorin particle. Administration of intermediate doses of hormone indicates that lipophorin is converted directly to the low density form; no appreciable amounts of intermediate density particles are formed.

Report this publication

Statistics

Seen <100 times