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Localization of tumor necrosis factor receptor messenger RNA in normal and herpes simplex virus-infected mouse eyes.

Authors
  • Cunningham, E T Jr
  • Stalder, A
  • Sanna, P P
  • Liu, S S
  • Bloom, F E
  • Howes, E L Jr
  • Campbell, I L
  • Margolis, T P
Type
Published Article
Journal
Investigative Ophthalmology & Visual Science
Publisher
Association for Research in Vision and Ophthalmology (ARVO)
Publication Date
Jan 01, 1997
Volume
38
Issue
1
Pages
9–15
Identifiers
PMID: 9008625
Source
Medline
License
Unknown

Abstract

The observed distribution of p75 and p55 TNFR mRNA in normal and acutely infected mouse eyes, and particularly over the heavily vascularized uveal tract and over cells at the vitreoretinal interface, supports a role for TNF as a mediator of intraocular inflammation, perhaps as a key regulator of the blood-ocular barrier.

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