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Localization of acid phosphatase activity in testosterone-treated prostatic urethra of human fetuses.

Authors
  • Kellokumpu-Lehtinen, P
Type
Published Article
Journal
The Prostate
Publication Date
Jan 01, 1983
Volume
4
Issue
3
Pages
265–270
Identifiers
PMID: 6844158
Source
Medline
License
Unknown

Abstract

Androgens accelerated differentiation of human fetal urethral epithelial cells into secretory prostatic cells in organ culture. These epithelial cells contained supranuclear Golgi complexes in which acid phosphatase enzyme activity could be demonstrated by an electron microscopic histochemical technique. Most of the acid phosphatase activity was localized in lysosomes. Some apical precipitates could also be seen. This apical activity might be in secretory granules. Also, mesenchymal cells contained this enzyme.

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