Local advantage: skin DCs prime; skin memory T cells protect
- Authors
- Type
- Published Article
- Journal
- Nature Immunology
- Publisher
- Springer Nature
- Publication Date
- May 01, 2009
- Volume
- 10
- Issue
- 5
- Pages
- 451–453
- Identifiers
- DOI: 10.1038/ni0509-451
- Source
- Springer Nature
- License
- Yellow
Abstract
How the immune system responds to local infection and establishes protective immunity in susceptible tissues remains unclear. Two new studies show that local tissue-resident dendritic cells prime cytotoxic T lymphocyte responses and that memory cytotoxic T lymphocytes remain in the tissue to provide antiviral immunity.
