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Local advantage: skin DCs prime; skin memory T cells protect

Authors
  • Iwasaki, Akiko1
Type
Published Article
Journal
Nature Immunology
Publisher
Springer Nature
Publication Date
May 01, 2009
Volume
10
Issue
5
Pages
451–453
Identifiers
DOI: 10.1038/ni0509-451
Source
Springer Nature
License
Yellow

Abstract

How the immune system responds to local infection and establishes protective immunity in susceptible tissues remains unclear. Two new studies show that local tissue-resident dendritic cells prime cytotoxic T lymphocyte responses and that memory cytotoxic T lymphocytes remain in the tissue to provide antiviral immunity.

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