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LL-37 as a therapeutic target for late stage prostate cancer.

Authors
  • Hensel, Jonathan A
  • Chanda, Diptiman
  • Kumar, Sanjay
  • Sawant, Anandi
  • Grizzle, William E
  • Siegal, Gene P
  • Ponnazhagan, Selvarangan
Type
Published Article
Journal
The Prostate
Publisher
Wiley (John Wiley & Sons)
Publication Date
May 01, 2011
Volume
71
Issue
6
Pages
659–670
Identifiers
DOI: 10.1002/pros.21282
PMID: 20957672
Source
Medline
License
Unknown

Abstract

CRAMP knock-down in a murine PCa model analogously demonstrated the tumorigenic contributions of LL-37 in PCa and its potential as a novel therapeutic target for the treatment of PCa and potentially, other cancers over-expressing the peptide.

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