The authors have presented an overview of indications and inclusion of patients to the liver transplant waiting list in the Brno transplant centre over a period of 30 years from the first liver transplant performed in the Czech Republic (the then Czechoslovakia). The first clinical liver transplant in the Czech Republic was performed on 2 February 1983. Indication for the transplant was a malignant liver tumour. For a period of 30 years (from 2 February 1983 to 15 January 2013) a total of 592 patients were placed on the waiting list and a total of 453 liver transplants were performed. An urgent liver transplant was carried out in 32 patients over the same period of time.