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Liver enzyme elevation and normal pulmonary function in an adult with a declining forced expiratory volume in 1 second.

Authors
  • Rider, Nicholas L
  • Craig, Timothy J
Type
Published Article
Journal
Allergy and asthma proceedings : the official journal of regional and state allergy societies
Publication Date
Jan 01, 2008
Volume
29
Issue
3
Pages
345–348
Identifiers
DOI: 10.2500/aap.2008.29.3120
PMID: 18534093
Source
Medline
License
Unknown

Abstract

This article presents a case report of a 41-year-old male firefighter with cholecystitis and a history of mildly elevated alanine aminotransferase. Liver biopsy showed periodic acid Schiff-positive, diastase-resistant periportal globules. Retrospective review of clinical data revealed progressive lung function decline despite absent pulmonary symptoms and normal pulmonary function testing. The following disorders should be considered in any patient with elevated transaminases without an apparent etiology: viral hepatitides, medication toxicity, autoimmune hepatitis, alcohol-induced hepatic injury, and alpha-1-antitrypsin deficiency.

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