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Live-cell monitoring of the glutathione-triggered release of the anticancer drug topotecan on gold nanoparticles in serum-containing media.

Authors
  • Kim, Mira
  • Ock, Kwangsu
  • Cho, Keunchang
  • Joo, Sang-Woo
  • Lee, So Yeong
Type
Published Article
Journal
Chemical Communications
Publisher
The Royal Society of Chemistry
Publication Date
May 04, 2012
Volume
48
Issue
35
Pages
4205–4207
Identifiers
DOI: 10.1039/c2cc30679d
PMID: 22441353
Source
Medline
License
Unknown

Abstract

The intracellular glutathione-triggered release of the anticancer drug topotecan from gold nanoparticles in serum-containing media was directly monitored in real time using a label-free fluorescence live-cell imaging technique.

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