Affordable Access

Access to the full text

Lithium Use and Non-use for Pregnant and Postpartum Women with Bipolar Disorder

Authors
  • Hermann, Alison1
  • Gorun, Alyson2
  • Benudis, Abigail1
  • 1 Weill Cornell Medical Center, Department of Psychiatry, 315 East 62nd Street, 5th Floor, New York, NY, 10065, USA , New York (United States)
  • 2 Columbia University Medical Center, Department of Psychiatry, New York, NY, USA , New York (United States)
Type
Published Article
Journal
Current Psychiatry Reports
Publisher
Springer-Verlag
Publication Date
Nov 07, 2019
Volume
21
Issue
11
Identifiers
DOI: 10.1007/s11920-019-1103-3
Source
Springer Nature
Keywords
License
Yellow

Abstract

Purpose of ReviewDespite being recognized as a first-line treatment for bipolar disorder, there is still inconsistent use of lithium in perinatal populations. This article will review data regarding lithium use during the peripartum and provide management recommendations for general psychiatric clinicians.Recent FindingsIn contrast to prior data, recent studies indicate that lithium use in pregnancy is associated with either no increased malformations risk or a small increase in risk for cardiac malformations including Ebstein’s anomaly. Limited data also show no significant effect on obstetric or neurodevelopmental outcomes. Data regarding infant lithium exposure via breastmilk remains limited.SummaryLithium is currently under-prescribed and is an important treatment for women with bipolar disorder in pregnancy and the postpartum. Clinicians must weigh the risk of lithium treatment versus the risk of withholding or changing lithium treatment when managing bipolar disorder in this population.

Report this publication

Statistics

Seen <100 times