Linear and nonlinear Raman microspectroscopy: History, instrumentation, and applications

Hideaki Kano; Hiroki Segawa; Philippe Leproux; Vincent Couderc

doi:10.1007/s10043-014-0123-9

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Linear and nonlinear Raman microspectroscopy: History, instrumentation, and applications

Authors

Kano, Hideaki¹
Segawa, Hiroki²
Leproux, Philippe³
Couderc, Vincent³

¹ University of Tsukuba, Institute of Applied Physics, Tsukuba, Ibaraki, 305-8573, Japan , Tsukuba, Ibaraki (Japan)
² The University of Tokyo, Department of Chemistry, School of Science, Bunkyo, Tokyo, 113-0033, Japan , Bunkyo, Tokyo (Japan)
³ Institut de Recherche XLIM, UMR CNRS No. 7252, Limoges Cedex, 87060, France , Limoges Cedex (France)

Type

Published Article

Journal

Optical Review

Publisher

The Optical Society of Japan

Publication Date

Nov 27, 2014

Volume

21

Issue

6

Pages

752–761

Identifiers

DOI: 10.1007/s10043-014-0123-9

Source

Springer Nature

Keywords

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Abstract

Through carrying out Raman spectroscopy under a microscope, we can observe the molecular distribution and dynamics of living cells in situ without staining or labeling. In general, Raman microscopy/microspectroscopy is classified into spontaneous Raman microscopy/microspectroscopy and nonlinear Raman microscopy/microspectroscopy. This review will first summarize the historical development of Raman microscopes, and will discuss in detail their instrumentation and applications.

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