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Levobupivacaine: a review of its use in regional anaesthesia and pain management.

Authors
  • Sanford, Mark
  • Keating, Gillian M
Type
Published Article
Journal
Drugs
Publication Date
Apr 16, 2010
Volume
70
Issue
6
Pages
761–791
Identifiers
DOI: 10.2165/11203250-000000000-00000
PMID: 20394458
Source
Medline
License
Unknown

Abstract

Levobupivacaine (Chirocaine) is a long-acting amide local anaesthetic that is effective when administered as an epidural, spinal, peripheral nerve or ocular block, or by topical application or local infiltration. In comparative trials, its clinical effects were not generally significantly different from those of bupivacaine or ropivacaine, although there was some variability in efficacy findings in different clinical populations. Levobupivacaine was generally well tolerated. Levobupivacaine provides effective anaesthesia and analgesia for a wide range of clinical populations and is a useful alternative to bupivacaine.

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