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Lessons learned from gene transfer approaches

Authors
  • Evans, Christopher H1
  • Ghivizzani, Steven C1
  • Lechman, Eric R1
  • Mi, Zhebao1
  • Jaffurs, Daniel1
  • Robbins, Paul D1
  • 1 University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA , Pittsburgh
Type
Published Article
Journal
Arthritis Research & Therapy
Publisher
Springer Science and Business Media LLC
Publication Date
Jul 08, 1999
Volume
1
Issue
1
Identifiers
DOI: 10.1186/ar6
Source
Springer Nature
Keywords
License
Yellow

Abstract

Recent technological advances allow the transfer of genes to the synovial lining of joints. As well as opening novel opportunities for therapy, these techniques provide valuable new tools for the study of synovitis and other aspects of the biology of joints in health and disease. This article reviews briefly the results of experiments in which selected genes have been transferred to the knee joints of healthy rabbits and rabbits with antigen-induced arthritis.

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