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Leptin, IL-10 and inflammatory markers (TNF-alpha, IL-6 and IL-8) in pre-eclamptic, normotensive pregnant and healthy non-pregnant women.

Authors
  • Sharma, Alpana
  • Satyam, Abhigyan
  • Sharma, Jai Bhagwan
Type
Published Article
Journal
American journal of reproductive immunology (New York, N.Y. : 1989)
Publication Date
Jul 01, 2007
Volume
58
Issue
1
Pages
21–30
Identifiers
PMID: 17565544
Source
Medline
License
Unknown

Abstract

Our findings suggest a relationship among TNF-alpha, IL-6, IL-8, IL-10 and leptin and indicate that altered levels of above markers in PE might be used as markers of pro-inflammation/anti-inflammation and endothelial dysfunction in pre-eclamptic pregnancies. These results also advocate the abnormal leptin and cytokine responses in mother, which might be involved in the pathogenesis of PE.

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