Affordable Access

deepdyve-link
Publisher Website

Left ventricular strains correlate with aortic elastic properties in adult patients with corrected tetralogy of Fallot (Results from the CSONGRAD Registry and MAGYAR-Path Study)

Authors
  • Rácz, Gergely
  • Kormányos, Árpád
  • Domsik, Péter
  • Kalapos, Anita
  • Gyenes, Nándor
  • Havasi, Kálmán
  • Ambrus, Nóra
  • Hartyánszky, István
  • Bogáts, Gábor
  • Nemes, Attila
Type
Published Article
Journal
Cardiovascular Diagnosis and Therapy
Publisher
AME Publishing Company
Publication Date
Apr 01, 2021
Volume
11
Issue
2
Pages
611–622
Identifiers
DOI: 10.21037/cdt-20-366
PMID: 33968638
PMCID: PMC8102256
Source
PubMed Central
Keywords
Disciplines
  • Original Article on Current Management Aspects in Adult Congenital Heart Disease (ACHD): Part III
License
Unknown

Abstract

Background Aortopathy is a common phenomenon in tetralogy of Fallot (TOF). The current study was designed to detect left ventricular (LV) deformation abnormalities and its relation to aortic stiffness in corrected TOF (cTOF) using the novel three-dimensional (3D) speckle-tracking echocardiography (3DSTE). Detailed comparative analysis between patients with early palliation-late correction (pcTOF) and early total reconstruction (etrTOF) was also performed. Methods The present study consisted of 28 cTOF patients (35.0±15.7 years, 11 males) from which 15 and 13 proved to be pcTOF and etrTOF, respectively. Their clinical parameters were compared to those of 39 matched healthy adults (35.5±6.0 years, 16 males). Results cTOF patients showed significantly lower global LV longitudinal, circumferential and area strains as compared to controls. In etrTOF patients, global LV 3D strain was higher than in controls. In pcTOF patients, all LV strains proved to be significantly lower as compared to those of etrTOF patients and controls. In all cTOF patients, several moderate correlations could be detected between LV strain parameters and aortic elastic properties. Conclusions Significant LV deformational abnormalities could be demonstrated in cTOF patients. etrTOF patients have beneficial LV strain parameters as compared to those of pcTOF patients. LV strains show correlations with aortic elastic properties.

Report this publication

Statistics

Seen <100 times