Here we present two cases of latex hypersensitivity. The clinical manifestations were conjunctivitis, urticaria, angioedema and dermatitis. The patients presented positive skin prick test (SPT) to latex with a commercial extract and by pricking through a latex surgical glove. Radioallergosorbent test (RAST) to latex and patch testing to common additives and to latex were negative. Skin prick tests with fruits (banana, kiwi, pineapple, apricot, avocado, grape) were positive but children presented no symptoms after ingestion of these fruits. These case reports are presented to heighten awareness of the potential of latex allergy also in children.