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Late cardiac deaths after isolated valve replacement for aortic stenosis. Relation to impaired left ventricular diastolic performance.

Authors
  • Lund, O
  • Jensen, F T
Type
Published Article
Journal
Angiology
Publication Date
Mar 01, 1989
Volume
40
Issue
3
Pages
199–208
Identifiers
PMID: 2916771
Source
Medline
License
Unknown

Abstract

Sixty-three patients took part in a follow-up study ten to seventeen years after valve replacement for aortic stenosis. Data obtained were used to predict cardiac deaths (n = 14) occurring in the following three-year period. The degree of residual left ventricular (LV) hypertrophy correlated inversely with indices for LV systolic and diastolic performance (radionuclide cardiography). A logistic regression (LR) model had a positive predictive value for cardiac deaths of 100% (10/10) with 8% (4/53) false negatives. Evaluating LV performance indices exclusively, LR analysis showed that only peak filling rate had independent predictive value. Subnormal and normal LV ejection fractions were associated with equal three-year cardiac death rates (29%). Depressed LV function was related to residual hypertrophy. Impaired diastolic performance was the prime predictor of cardiac deaths.

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