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Laser scanning confocal microscopy for conjunctival epithelium imaging.

Authors
  • Jürgens, Clemens
  • Rath, Robert
  • Giebel, Jürgen
  • Tost, Frank H W
Type
Published Article
Journal
Developments in ophthalmology
Publication Date
Jan 01, 2010
Volume
45
Pages
71–82
Identifiers
DOI: 10.1159/000315021
PMID: 20502028
Source
Medline
License
Unknown

Abstract

LSCM is a feasible method for examining the morphology of conjunctival epithelium using non-invasive in vivo imaging. Morphological criteria for squamous metaplasia of the conjunctiva in sicca syndrome are already known from cytology, and can be used in almost the same manner in LSCM. The separation of epithelial microcysts from small goblet cells is difficult with LSCM. Finally, the clinical application of LSCM in the staging of sicca syndrome has to be evaluated in future studies.

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