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Large intraperitoneal lipoleiomyoma in a pre-menopausal woman: a case report

Authors
  • Schaefer, Sara L.1
  • Strong, Amy L.1
  • Bahroloomi, Sheena1
  • Han, Jichang2
  • Whisman, Michella K.1
  • Wilkowski, Jodi M.1
  • Angeles, Christina V.1
  • 1 University of Michigan School of Medicine, 1500 E. Medical Center Drive, Ann Arbor, Michigan, 48109-5932, USA , Ann Arbor (United States)
  • 2 The Geisel School of Medicine at Dartmouth, 1 Rope Ferry Road, Hanover, New Hampshire, 03755, USA , Hanover (United States)
Type
Published Article
Journal
World Journal of Surgical Oncology
Publisher
Springer (Biomed Central Ltd.)
Publication Date
May 08, 2021
Volume
19
Issue
1
Identifiers
DOI: 10.1186/s12957-021-02256-9
Source
Springer Nature
Keywords
License
Green

Abstract

BackgroundLipoleiomyoma is a rare, benign variant of the commonplace uterine leiomyoma. Unlike leiomyoma, these tumors are composed of smooth muscle cells admixed with mature adipose tissue. While rare, they are most frequently identified in the uterus, but even more infrequently have been described in extrauterine locations.Case presentationWe describe a case report of a 45-year-old woman with a history of in vitro fertilization pregnancy presenting 6 years later with abdominal distention and weight loss found to have a 30-cm intra-abdominal lipoleiomyoma. While cross-sectional imaging can narrow the differential diagnosis, histopathological analysis with stains positive for smooth muscle actin, desmin, and estrogen receptor, but negative for HMB-45 confirms the diagnosis of lipoleiomyoma. The large encapsulated tumor was resected en bloc. The patients post-operative course was uneventful and her symptoms resolved.ConclusionsLipoleiomyoma should be considered on the differential diagnosis in a woman with a large intra-abdominal mass. While considered benign, resection should be considered if the mass is symptomatic, and the diagnosis is unclear or there is a concern for malignancy.

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