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A large conductance, voltage- and calcium-activated K+ channel in the basolateral membrane of rat enterocytes.

Authors
  • Morris, A P
  • Gallacher, D V
  • Lee, J A
Type
Published Article
Journal
FEBS Letters
Publisher
Wiley (John Wiley & Sons)
Publication Date
Sep 29, 1986
Volume
206
Issue
1
Pages
87–92
Identifiers
PMID: 2428663
Source
Medline
License
Unknown

Abstract

The patch-clamp technique was employed to record single channel currents in patches of basolateral membrane from enterocytes isolated from rat small intestine. We demonstrate the presence of a large conductance (250 pS), voltage- and calcium-activated, the maxi, K+ channel in this membrane. Currents in this K+ channel were blocked by the application of barium (5 mM) to the extracellular membrane face.

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