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The landscape of COVID‐19 trials in Australia

Authors
  • Seidler, Anna Lene
  • Aberoumand, Mason
  • Williams, Jonathan G
  • Aidan Tan
  • Hunter, Kylie E
  • Webster, Angela
Type
Published Article
Journal
Medical Journal of Australia
Publisher
AMPCo
Publication Date
Jul 24, 2021
Volume
215
Identifiers
DOI: 10.5694/mja2.51148
Source
MyScienceWork
License
Green

Abstract

This perspective explores the landscape of COVID-19 trials recruiting in Australia using trial registry data. We identified 56 trials addressing treatment and prevention of COVID-19, and 12 trials addressing indirect effects of the pandemic. Whilst there was substantial innovation in drug development and digital health, the potential of innovation in methodology, such as adaptive trials, remains largely untapped. Data sharing intentions were low, sample sizes were too small to detect differences in clinical outcomes, such as mortality, and lack of core outcome collection precludes evidence synthesis. Infrastructure for innovation would support coordination of research efforts, and reduce research waste.

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