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Landiolol, esmolol and propranolol protect from ischemia/reperfusion injury in isolated guinea pig hearts.

Authors
  • Kurosawa, Saori
  • Kanaya, Noriaki
  • Niiyama, Yukitoshi
  • Nakayama, Masayasu
  • Fujita, Satoshi
  • Namiki, Akiyoshi
Type
Published Article
Journal
Canadian journal of anaesthesia = Journal canadien d'anesthésie
Publication Date
May 01, 2003
Volume
50
Issue
5
Pages
489–494
Identifiers
PMID: 12734159
Source
Medline
License
Unknown

Abstract

The present study shows that landiolol, an ultra-short-acting cardioselective beta1 blocker, has cardioprotective effects on ischemia-reperfusion injury in isolated guinea pig hearts. All three beta blockers were equally protective but the intermediate dosage of landiolol preserved LVP during the pre-ischemic period.

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