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A Landau-Ginzburg Model of the Co-existence of Free Tubulin and Assembled Microtubules in Nucleation and Oscillations Phenomena.

Authors
  • Sept, D
  • Tuszyńskit, J A
Type
Published Article
Journal
Journal of biological physics
Publication Date
Mar 01, 2000
Volume
26
Issue
1
Pages
5–15
Identifiers
DOI: 10.1023/A:1005225911159
PMID: 23345708
Source
Medline
Keywords
License
Unknown

Abstract

A link is shown between reaction-diffusion kinetics for microtubuleassembly and time-dependent Landau-Ginzburg phenomenology. In the latter,microtubule assembly is treated as a first-order phase transition using apostulated Landau-Ginzburg free energy expansion. The results establish aconnection between the oscillations observed in experiment and the phasediagram for microtubule assembly. The model also predicts a specific heatbehavior which could be verified experimentally.

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