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Lacticacidosis after short-term infusion of propofol for anaesthesia in a child with osteogenesis imperfecta.

Authors
  • Kill, Clemens
  • Leonhardt, Andreas
  • Wulf, Hinnerk
Type
Published Article
Journal
Paediatric anaesthesia
Publication Date
Nov 01, 2003
Volume
13
Issue
9
Pages
823–826
Identifiers
PMID: 14617125
Source
Medline
License
Unknown

Abstract

We describe the case of a 7-year-old boy with osteogenesis imperfecta, who underwent anaesthesia with propofol-fentanyl-nitrous oxide-suxamethonium for orthopaedic surgery of a distal femur fracture. He developed lacticacidosis after short-term propofol infusion (150 min, mean infusion rate 13.5 mg.kg-1.h-1) associated with a prolonged recovery time without serious haemodynamic changes. The highest lactate concentration was 9.2 mmol.l-1 at 160 min after discontinuation of propofol. There was no significant increase in body temperature. The boy fully recovered.

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