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Lack of SOS repair in Streptococcus pneumoniae.

Authors
  • Gasc, A M
  • Sicard, N
  • Claverys, J P
  • Sicard, A M
Type
Published Article
Journal
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis
Publisher
Elsevier
Publication Date
Apr 01, 1980
Volume
70
Issue
2
Pages
157–165
Identifiers
PMID: 7374657
Source
Medline
License
Unknown

Abstract

Wild-type strains of Streptococcus pneumoniae were non-mutable by UV radiation and thymidine starvation. Moreover, UV-irradiated pneumococcal omega 2 phages were not reactivated in an irradiated host. This suggests that, in pneumoococcus, there is no efficient inducible repair process similar to the SOS repair described in detail for E. coli. We also report that mutations cannot be induced by a process thought to be linked to competence during transformation with isogenic wild-type DNA either on wild-type strains or in strains in which the hex function of excision and repair of mismatched bases is inactive.

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