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Lack of ecto-5'-nucleotidase (CD73) promotes arteriogenesis.

Authors
  • Böring, Yang Chul
  • Flögel, Ulrich
  • Jacoby, Christoph
  • Heil, Matthias
  • Schaper, Wolfgang
  • Schrader, Jürgen
Type
Published Article
Journal
Cardiovascular Research
Publisher
Oxford University Press
Publication Date
Jan 01, 2013
Volume
97
Issue
1
Pages
88–96
Identifiers
DOI: 10.1093/cvr/cvs286
PMID: 22977005
Source
Medline
License
Unknown

Abstract

Serial assessment of dynamic changes of vessel growth and metabolism in the process of arteriogenesis demonstrate that the lack of CD73-derived adenosine importantly promotes arteriogenesis but does not alter angiogenesis in our model of hindlimb ischaemia.

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