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Lack of cardioprotection from metabolic support with glutamine or glutamate in a porcine coronary occlusion model.

Authors
Type
Published Article
Journal
Scandinavian cardiovascular journal : SCJ
Publication Date
Volume
39
Issue
1-2
Pages
115–120
Identifiers
PMID: 16097425
Source
Medline
License
Unknown

Abstract

Substrate supplementation with the anaplerotic precursors glutamine and glutamate is ineffective as adjunctive therapy for severe myocardial ischemia. Beneficial effects documented in less complex experimental systems could not be transferred to a more pathophysiological relevant model.

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