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Labdanes and withanolides from Physalis coztomatl.

Authors
  • Pérez-Castorena, Ana-L
  • Oropeza, Ruth F
  • Vazquez, Alma R
  • Martínez, Mahinda
  • Maldonado, Emma
Type
Published Article
Journal
Journal of natural products
Publication Date
Jul 01, 2006
Volume
69
Issue
7
Pages
1029–1033
Identifiers
PMID: 16872139
Source
Medline
License
Unknown

Abstract

Aerial parts of Physalis coztomatl afforded a new labdane diterpene, physacoztomatin (1), and five new withanolides, physacoztolides A-E (5-9). Six known compounds were also isolated. The structures of the new compounds were established after analyses of their spectroscopic data and by means of chemical transformations. X-ray diffraction analyses of 15-dehydrophysacoztomatin (2) and 5 confirmed the structures of 1 and 5. Labd-13(E)-ene-8alpha,15-diol (4) and physacoztomatin (1) represent the first labdane diterpenes isolated from the genus Physalis.

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