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L-threo-3,4-dihydroxyphenylserine treatment for gait apraxia in parkinsonian patients.

Authors
  • Yoshida, M
  • Noguchi, S
  • Kuramoto, S
Type
Published Article
Journal
The Kurume medical journal
Publication Date
Jan 01, 1989
Volume
36
Issue
2
Pages
67–74
Identifiers
PMID: 2511378
Source
Medline
License
Unknown

Abstract

L-threo-3,4-dihydroxyphenylserine (L-DOPS) was administered to six parkinsonian patients for the treatment of gait related akinesia which was refractile to L-DOPA treatment. One responded with marked improvement and one with only mild improvement. Although number of patients who respond markedly to this noradrenaline precursor, L-DOPS, is limited, L-DOPS was felt to be the most effective treatment modality for L-DOPA refractile gait related akinesia and L-DOPA related orthostatic hypotension.

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