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l-folinic acid versus d,l-folinic acid in rescue of high-dose methotrexate therapy in children.

Authors
  • Etienne, M C
  • Thyss, A
  • Bertrand, Y
  • Touraine, R
  • Rubie, H
  • Robert, A
  • Milano, G
Type
Published Article
Journal
Journal of the National Cancer Institute
Publication Date
Aug 05, 1992
Volume
84
Issue
15
Pages
1190–1195
Identifiers
PMID: 1635087
Source
Medline
License
Unknown

Abstract

The administration of the pure l-FA, compared with the administration of the racemic mixture, results in comparable blood profiles of active folates and MTX, leads to equivalent treatment tolerance, and avoids the plasma accumulation of d-FA.

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