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Kinetics of disappearance of resistance mutations and reappearance of wild-type during structured treatment interruptions.

Authors
  • Halfon, Philippe
  • Durant, Jacques
  • Clevenbergh, Philippe
  • Carsenti, Hélène
  • Celis, Linda
  • Khiri, Hacene
  • De Smet, Koen
  • De Brauwer, Annelies
  • Hulstaert, Frank
  • Dellamonica, Pierre
Type
Published Article
Journal
AIDS
Publisher
Ovid Technologies (Wolters Kluwer) - Lippincott Williams & Wilkins
Publication Date
Jun 13, 2003
Volume
17
Issue
9
Pages
1351–1361
Identifiers
PMID: 12799556
Source
Medline
License
Unknown

Abstract

The determination of the timepoint at which a virus population of an HIV-1 patient undergoing STI reverts to WT is dependent on the assay used. The viral load increase in most patients is compatible with the outgrowth of virus with fewer or no mutations.

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