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Kaliopenic nephropathy revisited.

Authors
  • Elitok, Saban1
  • Bieringer, Markus1
  • Schneider, Wolfgang1
  • Luft, Friedrich C1
  • 1 Division of Nephrology, Helios-Klinikum Berlin , and Experimental and Clinical Research Center, a joint cooperation of the Max-Delbrück Center for Molecular Medicine and the Charité Medical Faculty , Berlin-Buch , Germany. , (Germany)
Type
Published Article
Journal
Clinical kidney journal
Publication Date
Aug 01, 2016
Volume
9
Issue
4
Pages
543–546
Identifiers
DOI: 10.1093/ckj/sfv154
PMID: 27478593
Source
Medline
Keywords
License
Unknown

Abstract

In the 'older' literature, a definitive renal pathology was described in patients with long-standing hypokalaemia and depletion of the body's potassium reserves. The topic is relevant because possibly a quite cheaply reversible element in the course of chronic kidney disease progression could be addressed. Earlier, pathologists drew attention to vacuolar changes in renal tubular epithelium accompanied by inflammatory interstitial changes in patients with potassium losses. The diagnostic term 'kaliopenic nephropathy' was coined to describe such patients. Kaliopenic nephropathy now receives less emphasis than in earlier times. However, with eating disorders, laxative abuse and other potential causes, we suggest that the syndrome should be resurrected.

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