Juvenile ankylosing spondylitis has its onset in childhood. Aortic insufficiency occurs in children and may precede the onset of symptoms of spondylitis. It may first be seen as peripheral arthritis and aortic valvulitis before clinically evident sacroiliitis is apparent. The HLA B27 marker makes it possible to identify those patients at increased risk for development of ankylosing spondylitis.
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This record was last updated on 07/01/2016 and may not reflect the most current and accurate biomedical/scientific data available from NLM.
The corresponding record at NLM can be accessed at https://www.ncbi.nlm.nih.gov/pubmed/7279473