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Not just for tumor targeting : unmet medical needs and opportunities for nanomedicine

Authors
  • Lepeltier, Elise Anne
  • Nuhn, Lutz
  • Lehr, Claus-Michael
  • Zentel, Rudolf
Publication Date
Jan 01, 2015
Source
Ghent University Institutional Archive
Keywords
Language
English
License
Unknown
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Abstract

During the last 3 decades nanomedicines have provided novel opportunities to improve the delivery of chemotherapeutics in cancer therapy effectively. However, many principles learnt from there have the potential to be transferred to other diseases. This perspective article, on the one hand, critically reflects the limitations of nanomedicines in tumor therapy and, on the other hand, provides alternative examples of nanomedicinal applications in immunotherapy, noninvasive drug deliveries across epithelial barriers and strategies to combat intra- and extracellular bacterial infections. Looking ahead, access to highly complex nanoparticular delivery vehicles given nowadays may allow further improved therapeutic concepts against several diseases in the future too.

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