The anniversary of one hundred years from the birth of Josef Hynie, the renowned professor of Charles' University and pioneer of medical sexology, is an impulse for thinking again about his lifelong successful creative activities, namely clinical, scientific, publication, teaching and sexual-educational activities. At the Faculty of Medicine in Prague Hynie enforced and built the first university sexological institute in the world and achieved its general recognition. With the team of his pupils for years he integrated the behavioral and reproduction aspects of the branch and thus predetermined its wide conception also for the future generations of Czech sexologists. In 1981 Hynie's efforts were crowned by definitive inclusion of medical sexology into the Czechoslovak health care system of that time. The authors pay attention also to his unforgettable, excellent character traits. The biographical treatise is framed up in an authentic remembrance of MUDr. Jaroslava Pondĕlícková-Maslová, his colleague for many years, and enlivened by photographs of that period.