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It’s not just a phase: function and characteristics of RNA-binding proteins in phase separation

Authors
  • Wiedner, Hannah J.1, 1
  • Giudice, Jimena1, 1, 1
  • 1 University of North Carolina at Chapel Hill, Chapel Hill, NC, USA , Chapel Hill (United States)
Type
Published Article
Journal
Nature Structural & Molecular Biology
Publisher
Springer Nature
Publication Date
Jun 07, 2021
Volume
28
Issue
6
Pages
465–473
Identifiers
DOI: 10.1038/s41594-021-00601-w
Source
Springer Nature
Disciplines
  • review-article
License
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Abstract

The organization of multiple steps of the RNA life cycle in phase-separated condensates presents a framework for understanding how sequestration of RNA-binding proteins and RNAs modulates gene expression.

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