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Itraconazole in the treatment of acute vaginal candidiasis.

Authors
  • Bloch, B
  • Barnard, P G
  • Burger, G D
  • Meyer, J S
  • Parkes, J R
  • Smythe, E
Type
Published Article
Journal
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde
Publication Date
Feb 06, 1988
Volume
73
Issue
3
Pages
172–173
Identifiers
PMID: 2829371
Source
Medline
License
Unknown

Abstract

In a multicentre open prospective study itraconazole was evaluated in the treatment of acute vaginal candidiasis. Two dosage regimens were tested--200 mg twice a day for 1 day and 200 mg twice a day for 2 days. There were no statistically significant differences between these dosages, and cure rates at 7 and 28 days after treatment were 83% and 75% respectively. These are marginally lower than those produced by longer courses of oral ketoconazole (Nizoral; Janssen) and vaginal econazole nitrate but the advantages are better patient compliance and greater cost-effectiveness.

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