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The itchy scalp--scratching for an explanation.

Authors
  • Bin Saif, Ghada A
  • Ericson, Marna E
  • Yosipovitch, Gil
Type
Published Article
Journal
Experimental Dermatology
Publisher
Wiley (Blackwell Publishing)
Publication Date
Dec 01, 2011
Volume
20
Issue
12
Pages
959–968
Identifiers
DOI: 10.1111/j.1600-0625.2011.01389.x
PMID: 22092575
Source
Medline
License
Unknown

Abstract

Scalp pruritus is a common complaint that is considered a diagnostically and therapeutically challenging situation. Scalp skin has a unique neural structure that contains densely innervated hair follicles and dermal vasculature. In spite of the recent advances in our understanding of itch pathophysiology, scalp itching has not been studied as yet. In this review, we summarize the current knowledge on the neurobiology of scalp and hair follicles as well as itch mediators and provide a putative mechanism for scalp itch with special emphasis on neuroanatomy and pathophysiology.

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