Affordable Access

deepdyve-link deepdyve-link
Publisher Website

Isopropanol protein precipitation for the analysis of plasma free metanephrines by liquid chromatography-tandem mass spectrometry.

Authors
  • Marney, Luke C
  • Laha, Thomas J
  • Baird, Geoffrey S
  • Rainey, Petrie M
  • Hoofnagle, Andrew N
Type
Published Article
Journal
Clinical Chemistry
Publisher
American Association for Clinical Chemistry
Publication Date
Oct 01, 2008
Volume
54
Issue
10
Pages
1729–1732
Identifiers
DOI: 10.1373/clinchem.2008.104083
PMID: 18687739
Source
Medline
License
Unknown

Abstract

Isopropanol protein precipitation is a novel and effective off-line sample preparation method for metanephrines that offers a less expensive alternative to on-line solid-phase extraction for low-volume testing and requires a sample volume of only 200 microL. The mass spectrometric analysis time is equivalent to that of solid-phase techniques.

Report this publication

Statistics

Seen <100 times